Hemolysin of uropathogenic Escherichia coli: A cloak or a dagger?
نویسندگان
چکیده
منابع مشابه
Cloak-and-dagger publishing.
71 SPECIALSECTION could escape from a lab and cause a human pandemic, or that revealing details about the research could inadvertently aid terrorists seeking a bioweapon. They asked the National Science Advisory Board for Biosecurity, set up after the 2001 anthrax attacks, to review the H5N1 studies. It initially recommended that the papers be published only if journal editors deleted key metho...
متن کاملMolecular Characterization and Antimicrobial Resistance of Uropathogenic Escherichia coli
Background:Urinary Tract Infections (UTIs) are the most common infectious diseases in childhood. The Uropathogenic Escherichia coli (UPEC) strains account for as much as 80% of UTIs. Objective:From a clinical perspective, it is important to know which virulence factors and antibiotic resistance properties are present in UPEC strains in pediatrics. Therefore, this study was carried out...
متن کاملMultiple copies of hemolysin genes and associated sequences in the chromosomes of uropathogenic Escherichia coli strains.
The O6 serogroup Escherichia coli strain 536 carries two hemolysin (hly) determinants integrated into the chromosome. The two hly determinants are not completely identical, either functionally or structurally, as demonstrated by spontaneous deletion mutants carrying only one of them and by cloning each of the two determinants separately into cosmid vectors. Each hly determinant is independently...
متن کاملRole of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli.
Bacterial pathogens produce a variety of exotoxins, which often become associated with the bacterial outer membrane component lipopolysaccharide (LPS) during their secretion. LPS is a potent proinflammatory mediator; however, it is not known whether LPS contributes to cell signaling induced by those microbial components to which it is attached. This is partly due to the common view that LPS pre...
متن کاملDetermination of phenotypic expression of the fimbriae and hemolysin of uropathogenic Escherichia coli (UPEC)
These E. coli are primarily derived from the faecal flora, which can colonize the periurethral area, overcome the local host defences and enter and multiply within the urinary tract. These E. coli strains are designed as Uropathogenic E. Coli (UPEC) which possess distinctive traits that confer an enhanced extraintestinal virulence potential. 4-6 UTI is predominantly a disease of the females, be...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2016
ISSN: 0005-2736
DOI: 10.1016/j.bbamem.2015.08.015